Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 17/20 | 0.61 |
| ▸ | ACE | P12821 | 15/20 | 0.61 |
| ▸ | ACE2 | Q9BYF1 | 8/20 | 0.43 |
| ▸ | CPA1 | P15085 | 7/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567664 | 1.00 | MME (0.61) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL7567007 | 0.94 | MME (0.58) | MMEACEACE2CPA1 | |
| SCHEMBL7566998 | 0.94 | MME (0.58) | MMEACEACE2CPA1 | |
| SCHEMBL7567282 | 0.94 | MME (0.62) | MMEACEACE2CPA1 | |
| SCHEMBL7567275 | 0.94 | MME (0.62) | MMEACEACE2CPA1 | |
| SCHEMBL8450819 | 0.91 | MME (0.50) | MMEACECPA1ITGB3ITGAV | |
| SCHEMBL8027176 | 0.90 | MME (0.73) | MMEACEACE2CPA1 | |
| SCHEMBL7569066 | 0.87 | MME (0.67) | MMEACEACE2CPA1 | |
| SCHEMBL7569072 | 0.87 | MME (0.67) | MMEACEACE2CPA1 | |
| SCHEMBL8453133 | 0.87 | MME (0.49) | MMEACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |