Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.50 |
| ▸ | ACE | P12821 | 5/20 | 0.50 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | CPA2 | P48052 | 1/20 | 0.38 |
| ▸ | CPA4 | Q9UI42 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8453133 | 0.95 | MME (0.49) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL8446428 | 0.95 | MME (0.52) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL7567672 | 0.91 | MME (0.61) | MMEACECPA1ITGB3ITGAV | |
| SCHEMBL7567664 | 0.91 | MME (0.61) | MMEACECPA1ITGB3ITGAV | |
| SCHEMBL8446420 | 0.88 | MME (0.50) | MMEACETACR1CTSBMEN1 | |
| SCHEMBL7567007 | 0.87 | MME (0.58) | MMEACEKMT2ACPA1CPA2 | |
| SCHEMBL7566998 | 0.87 | MME (0.58) | MMEACEKMT2ACPA1CPA2 | |
| SCHEMBL7567282 | 0.87 | MME (0.62) | MMEACECPA1 | |
| SCHEMBL7567275 | 0.87 | MME (0.62) | MMEACECPA1 | |
| SCHEMBL8446409 | 0.87 | MME (0.60) | MMEACETACR1CTSBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |