Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | NQO2 | P16083 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10866827 | 0.91 | ALDH1A1 (0.63) | ALDH1A1NQO2POLBMAPTRAB9A | |
| SCHEMBL5886271 | 0.86 | ALDH1A1 (0.54) | ALDH1A1NQO2POLBMAPTRAB9A | |
| SCHEMBL11198221 | 0.84 | ALDH1A1 (0.58) | ALDH1A1MAPTRAB9ANPC1LMNA | |
| SCHEMBL13439501 | 0.83 | NQO2 (0.84) | ALDH1A1NQO2POLBMAPTRAB9A | |
| SCHEMBL31598647 | 0.83 | NQO2 (0.62) | ALDH1A1NQO2POLBMAPTRAB9A | |
| SCHEMBL7564782 | 0.82 | ALDH1A1 (0.64) | ALDH1A1NQO2POLBMAPTLMNA | |
| SCHEMBL7566381 | 0.81 | KDM4E (0.55) | ALDH1A1NQO2POLBRAB9ANPC1 | |
| SCHEMBL31659336 | 0.81 | KMT2A (0.63) | ALDH1A1NQO2POLBMAPTRAB9A | |
| SCHEMBL5886316 | 0.81 | ALDH1A1 (0.51) | ALDH1A1NQO2POLBMAPTRAB9A | |
| Acetic Acid SCHEMBL28270696 | 0.81 | NQO2 (0.80) | ALDH1A1NQO2POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| US-6114332-A | BACTERICIDES | XENOVA LIMITED (GB) | 2000-09-05 | — | — | US | disclosed |
| EP-0934278-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998017650-A1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LIMITED (GB) | 1998-04-30 | — | — | WO | disclosed |
| EP-0172744-A2 | Phenazinecarboxamide compounds | DEVELOPMENT FINANCE CORPORATION OF NEW ZEALAND (NZ) | 1986-02-26 | — | — | EP | disclosed |
| EP-0081338-A1 | N-(tetraxol-5-yl)phenazine-1-carboxamides | RIKER LABORATORIES, INCORPORATED (US) | 1983-06-15 | — | — | EP | disclosed |
| US-4377579-A | ANTIALLERGENS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1983-03-22 | — | — | US | disclosed |