SCHEMBL7567889

SCHEMBL7567889

CC(C)(C)OC(=O)C(C=O)C1CCNCC1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CPN1 P15169 1/20 0.33
CPB2 Q96IY4 1/20 0.33
SLC6A2 P23975 3/20 0.33
SLC6A4 P31645 3/20 0.33
SLC6A3 Q01959 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28177533 0.88 CTSK (0.33)
SCHEMBL28996779 0.81
SCHEMBL28996778 0.81
SCHEMBL4565414 0.78 CPN1 (0.36) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL27511091 0.78 CPN1 (0.36) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL412203 0.78 CPN1 (0.36) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL27530237 0.77 CPN1 (0.35) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL854892 0.77 DPP4 (0.37) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL4431392 0.77 CPN1 (0.35) CPN1CPB2SLC6A2SLC6A4SLC6A3
SCHEMBL1129311 0.75 CPN1 (0.41) CPN1CPB2SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1173170-A4 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO INC (US) 2002-05-29 EP disclosed
EP-1173170-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Merck & Co., Inc. (US) 2002-01-23 EP disclosed
WO-2000059503-A1 PYRROLIDINE MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY MERCK & CO., INC. (US) 2000-10-12 WO disclosed