Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 15/20 | 0.47 |
| ▸ | F12 | P00748 | 1/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 8/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.44 |
| ▸ | F2 | P00734 | 6/20 | 0.44 |
| ▸ | KLK1 | P06870 | 4/20 | 0.44 |
| ▸ | PLAT | P00750 | 6/20 | 0.40 |
| ▸ | LCK | P06239 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7561439 | 0.99 | PLAU (0.46) | PLAUF12ST14KDM4EALDH1A1 | |
| SCHEMBL7562958 | 0.87 | F12 (0.45) | PLAUF12ST14PLGPRSS1 | |
| Hydrochloric Acid SCHEMBL7561887 | 0.86 | F12 (0.44) | PLAUF12ST14PLGPRSS1 | |
| SCHEMBL7564455 | 0.83 | KDM4E (0.51) | PLAUF12ST14KDM4EALDH1A1 | |
| SCHEMBL7564845 | 0.81 | FTO (0.43) | PLAUF12ST14KDM4EALDH1A1 | |
| SCHEMBL18720234 | 0.79 | F12 (0.46) | PLAUF12ST14KDM4EALDH1A1 | |
| SCHEMBL23499977 | 0.78 | KDM4E (0.72) | KDM4EALDH1A1GLAGAAHPGD | |
| Hydrochloric Acid SCHEMBL7564086 | 0.78 | PRSS1 (0.44) | PLAUF12ST14ALDH1A1PLG | |
| Hydrochloric Acid SCHEMBL7561950 | 0.78 | KDM4E (0.42) | PLAUKDM4EALDH1A1GLAGAA | |
| SCHEMBL29625781 | 0.75 | LCK (0.56) | PLAUKDM4EALDH1A1GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802179-B1 | SUBSTITUTED AMIDINONAPHTHYL ESTER DERIVATIVES | TORII PHARMACEUTICAL CO LTD (JP) | 2002-08-21 | — | — | EP | disclosed |
| US-5885990-A | FIBRINOLYSIS PROMOTING ACTION; THROMBOLYSIS ACTION | TORII PHARMACEUTICAL CO., LTD. (JP) | 1999-03-23 | — | — | US | disclosed |
| EP-0802179-A1 | SUBSTITUTED AMIDINONAPHTHYL ESTER DERIVATIVES | TORII PHARMACEUTICAL CO., LTD. (JP) | 1997-10-22 | — | — | EP | disclosed |