Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11881419 | 0.78 | MEN1 (0.34) | MEN1LMNAKMT2A | |
| SCHEMBL2699373 | 0.77 | — | — | |
| SCHEMBL11125082 | 0.73 | MEN1 (0.32) | MEN1LMNAKMT2A | |
| SCHEMBL14620750 | 0.72 | MEN1 (0.31) | MEN1LMNAKMT2A | |
| SCHEMBL2696185 | 0.71 | CYP3A4 (0.31) | MEN1KMT2A | |
| SCHEMBL1964307 | 0.71 | — | — | |
| SCHEMBL4396504 | 0.68 | NPSR1 (0.30) | — | |
| SCHEMBL4187679 | 0.68 | MEN1 (0.36) | MEN1LMNAKMT2A | |
| SCHEMBL28724654 | 0.67 | ALDH1A1 (0.38) | MEN1LMNAKMT2A | |
| SCHEMBL2153330 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242366-A1 | SALICYLAMIDES AS SERINE PROTEASE AND FACTOR XA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001044172-A1 | SALICYLAMIDES AS SERINE PROTEASE AND FACTOR XA INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-06-21 | — | — | WO | disclosed |