Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28515052 | 0.86 | TSHR (0.38) | ALDH1A1TSHRMAPTLMNAMEN1 | |
| SCHEMBL4247813 | 0.86 | TSHR (0.38) | ALDH1A1TSHRMAPTLMNAMEN1 | |
| SCHEMBL4851503 | 0.79 | TSHR (0.38) | ALDH1A1TSHRMAPK1SMN1; SMN2LMNA | |
| SCHEMBL4850104 | 0.78 | TDP1 (0.33) | MAPTCYP19A1POLBRAB9A | |
| SCHEMBL18053347 | 0.77 | TSHR (0.40) | TSHRMAPTLMNAMEN1KMT2A | |
| SCHEMBL5419515 | 0.76 | CYP19A1 (0.33) | KMT2ACYP19A1 | |
| SCHEMBL3926283 | 0.75 | SLC6A3 (0.40) | ALDH1A1TSHRGLAMAPK1CYP19A1 | |
| SCHEMBL996860 | 0.75 | SLC6A3 (0.40) | ALDH1A1TSHRGLAMAPK1CYP19A1 | |
| SCHEMBL31064743 | 0.75 | SLC6A3 (0.40) | ALDH1A1TSHRGLAMAPK1CYP19A1 | |
| SCHEMBL601985 | 0.74 | CYP19A1 (0.38) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002068527-A2 | NOVEL β-OXO COMPOUNDS AND THEIR USE IN PHOTORESIST | ARCH SPECIALTY CHEMICALS, INC. (US) | 2002-09-06 | — | — | WO | disclosed |