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Sugi Predict / Compounds / SCHEMBL7568360

SCHEMBL7568360

SCHEMBL7568360

CC(C)CN(CCC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc1ccc(-c2ccccc2)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 12/20 0.66
▸ ACE P12821 11/20 0.66
▸ CTSB P07858 1/20 0.51
▸ ACE2 Q9BYF1 6/20 0.48
▸ CPA1 P15085 5/20 0.48
▸ GPR34 Q9UPC5 2/20 0.46
▸ ITGB3 P05106 1/20 0.45
▸ ITGAV P06756 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7567838 1.00 MME (0.66) MMEACECTSBACE2CPA1
SCHEMBL7567698 0.95 MME (0.59) MMEACECTSBACE2CPA1
SCHEMBL8452063 0.94 MME (0.57) MMEACECTSB
SCHEMBL8451194 0.94 MME (0.57) MMEACECTSB
SCHEMBL7567870 0.93 MME (0.61) MMEACECTSBACE2CPA1
SCHEMBL7570511 0.92 MME (0.55) MMEACECTSB
SCHEMBL7574613 0.92 MME (0.55) MMEACECTSBACE2CPA1
SCHEMBL7574618 0.92 MME (0.55) MMEACECTSBACE2CPA1
SCHEMBL7565484 0.91 MME (0.67) MMEACECTSBACE2CPA1
SCHEMBL7569387 0.91 MME (0.67) MMEACECTSBACE2CPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0798291-B1 NOVEL 1,3-DIALKYLUREA DERIVATIVES SANTEN PHARMACEUTICAL CO LTD (JP) 2002-09-11 — — EP disclosed
EP-0798291-A1 NOVEL 1,3-DIALKYLUREA DERIVATIVES SANTEN PHARMACEUTICAL CO., LTD. (JP) 1997-10-01 — — EP disclosed