Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.55 |
| ▸ | ACE | P12821 | 4/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 5/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | FCER2 | P06734 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8451194 | 0.92 | MME (0.57) | MMEACECTSB | |
| SCHEMBL8452063 | 0.92 | MME (0.57) | MMEACECTSB | |
| SCHEMBL7567838 | 0.92 | MME (0.66) | MMEACECTSB | |
| SCHEMBL7568360 | 0.92 | MME (0.66) | MMEACECTSB | |
| SCHEMBL7573208 | 0.88 | MME (0.64) | MMEACECTSBHPGDSMMP1 | |
| SCHEMBL8452065 | 0.87 | MME (0.54) | MMEACECTSB | |
| SCHEMBL8446424 | 0.87 | MME (0.54) | MMEACECTSB | |
| SCHEMBL8446430 | 0.87 | MME (0.52) | MMEACECTSB | |
| SCHEMBL7567698 | 0.87 | MME (0.59) | MMEACECTSB | |
| SCHEMBL8452240 | 0.87 | MME (0.50) | MMEACECTSBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |