SCHEMBL7568539

SCHEMBL7568539

COc1ccc(COC2CNCCC2c2ccc(Br)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
REN P00797 17/20 0.79
FPR1 P21462 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6041309 0.89 REN (0.80) REN
SCHEMBL6042777 0.88 REN (1.00) RENFPR1
SCHEMBL6041904 0.88 REN (0.79) REN
SCHEMBL6041925 0.88 REN (1.00) RENFPR1
SCHEMBL6041618 0.88 REN (1.00) RENFPR1
SCHEMBL6956168 0.88 REN (0.78) REN
SCHEMBL6951046 0.83 REN (0.78) REN
SCHEMBL6043533 0.81 REN (1.00) REN
SCHEMBL6043191 0.81 REN (1.00) REN
SCHEMBL6041696 0.81 REN (1.00) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002076440-A2 METHODS OF TREATING ALZHEIMER'S DISEASE WITH PIPERIDIN DERIVATES ELAN PHARMACEUTICALS, INC. (US) 2002-10-03 WO disclosed