Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KIF5B | P33176 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8073459 | 0.98 | HSD17B10 (0.46) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL18427395 | 0.83 | TSHR (0.48) | HSD17B10TSHRALDH1A1MAPTGAA | |
| SCHEMBL6321756 | 0.81 | HSD17B10 (0.46) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL1702377 | 0.81 | HSD17B10 (0.46) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL10255934 | 0.79 | MAPT (0.53) | CYP3A4MAPTGAAGLAEPHX1 | |
| Hydrochloric Acid SCHEMBL4679683 | 0.79 | HSD17B10 (0.45) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL15934314 | 0.76 | HSD17B10 (0.50) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL10985595 | 0.74 | MAPT (0.41) | TSHRALDH1A1TDP1MAPTGAA | |
| Sulfuric Acid SCHEMBL6321163 | 0.74 | HSD17B10 (0.39) | HSD17B10TSHRALDH1A1CYP3A4TDP1 | |
| SCHEMBL11289947 | 0.71 | CYP3A4 (0.53) | HSD17B10TSHRALDH1A1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0959067-B1 | Process for the preparation of aryl hydrazines | CLARIANT GMBH (DE) | 2002-09-11 | — | — | EP | claimed |
| WO-2001002351-A2 | METHOD FOR PREPARING A HYDROXYLATED ARYLHYDRAZINE, INTERMEDIATE PRODUCTS AND METHOD FOR OBTAINING SAME | RHODIA CHIMIE (FR) | 2001-01-11 | — | — | WO | disclosed |
| US-6057478-A | Process for preparing arylhydrazines | CLARIANT GMBH (DE) | 2000-05-02 | — | — | US | disclosed |