Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568658 | 0.81 | MAPK14 (0.43) | MAPK14MAPK13MAPK12MAPK11PIK3CA | |
| SCHEMBL7079261 | 0.78 | MAPK14 (0.53) | MAPK14MAPK13MAPK12MAPK11PIK3CA | |
| SCHEMBL7080292 | 0.74 | MAPK14 (0.69) | MAPK14MAPK13MAPK12MAPK11PIK3CA | |
| SCHEMBL7568661 | 0.74 | MAPK14 (0.42) | MAPK14MAPK13MAPK12MAPK11PIK3CA | |
| SCHEMBL7080464 | 0.74 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7079458 | 0.73 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11PIK3CA | |
| SCHEMBL7079819 | 0.71 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11MAOB | |
| SCHEMBL7079670 | 0.68 | MAPK14 (0.50) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7079301 | 0.66 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7080338 | 0.66 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |