Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.34 |
| ▸ | RASGRP3 | Q8IV61 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569354 | 0.92 | TDP1 (0.35) | ALDH1A1MAPTKDM4EHPGDTSHR | |
| SCHEMBL11983659 | 0.91 | TDP1 (0.36) | ALDH1A1MAPTKDM4EHPGDTSHR | |
| SCHEMBL12952370 | 0.89 | TDP1 (0.33) | ALDH1A1MAPTKDM4EHSD17B10MAPK1 | |
| SCHEMBL7568969 | 0.87 | PTPN1 (0.34) | ALDH1A1MAPTKDM4ETSHRHSD17B10 | |
| SCHEMBL15470786 | 0.85 | TDP1 (0.31) | MAPK1TDP1 | |
| SCHEMBL10102271 | 0.85 | MEN1 (0.34) | ALDH1A1MAPTKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL13659148 | 0.84 | TDP1 (0.30) | MAPK1TDP1 | |
| SCHEMBL15470789 | 0.83 | TDP1 (0.32) | MAPK1TDP1 | |
| SCHEMBL15470794 | 0.81 | — | — | |
| SCHEMBL12588656 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984929-B1 | NAPHTHOPYRAN DERIVATIVES, COMPOSITIONS AND (CO)POLYMER MATRICES CONTAINING THE SAME | CORNING SA (FR) | 2002-09-11 | — | — | EP | claimed |