Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 4/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.44 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.44 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.44 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.44 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.44 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7569034 | 1.00 | CTRB1 (0.49) | CTRB1MEN1KMT2ANPSR1CTSK | |
| SCHEMBL7569039 | 1.00 | CTRB1 (0.49) | CTRB1MEN1KMT2ANPSR1CTSK | |
| SCHEMBL7398974 | 0.88 | CTRB1 (0.60) | CTRB1MEN1KMT2ANPSR1CTSK | |
| SCHEMBL14069202 | 0.88 | CTRB1 (0.60) | CTRB1MEN1KMT2ANPSR1CTSK | |
| SCHEMBL7398976 | 0.88 | CTRB1 (0.60) | CTRB1MEN1KMT2ANPSR1CTSK | |
| SCHEMBL6588325 | 0.81 | CTRB1 (0.57) | CTRB1CTSKCTSLHRH1OPRK1 | |
| SCHEMBL7361852 | 0.80 | CTRB1 (0.64) | CTRB1CTSKCTSLOPRK1CTSB | |
| SCHEMBL7361850 | 0.80 | CTRB1 (0.64) | CTRB1CTSKCTSLOPRK1CTSB | |
| SCHEMBL7397704 | 0.78 | CYP2C19 (0.53) | MEN1KMT2ACYP2C19PRMT5WDR77 | |
| SCHEMBL7397707 | 0.78 | CYP2C19 (0.53) | MEN1KMT2ACYP2C19PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997046553-A1 | THROMBIN INHIBITORS | NOVARTIS AG (CH) | 1997-12-11 | — | — | WO | disclosed |