⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6118063 | 0.79 | USP2 (0.48) | — | |
| SCHEMBL4465842 | 0.79 | USP2 (0.48) | — | |
| SCHEMBL4465846 | 0.79 | USP2 (0.48) | — | |
| SCHEMBL6100147 | 0.77 | — | — | |
| SCHEMBL4730737 | 0.77 | — | — | |
| SCHEMBL11829047 | 0.74 | — | — | |
| SCHEMBL18954410 | 0.74 | — | — | |
| SCHEMBL29111714 | 0.74 | — | — | |
| SCHEMBL29059948 | 0.74 | — | — | |
| SCHEMBL30711 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912536-B1 | TAXANE HYDROXY MONOACYLATION METHOD | AVENTIS PHARMA SA (FR) | 2002-06-05 | — | — | EP | claimed |
| EP-0912536-A1 | TAXANE HYDROXY MONOACYLATION METHOD | Aventis Pharma S.A. (FR) | 1999-05-06 | — | — | EP | claimed |
| WO-1998001435-A1 | TAXANE HYDROXY MONOACYLATION METHOD | RHONE-POULENC RORER S.A. (FR) | 1998-01-15 | — | — | WO | claimed |
| EP-0912536-B1 | TAXANE HYDROXY MONOACYLATION METHOD | AVENTIS PHARMA SA (FR) | 2002-06-05 | — | — | EP | disclosed |
| EP-0912536-A1 | TAXANE HYDROXY MONOACYLATION METHOD | Aventis Pharma S.A. (FR) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998001435-A1 | TAXANE HYDROXY MONOACYLATION METHOD | RHONE-POULENC RORER S.A. (FR) | 1998-01-15 | — | — | WO | disclosed |