Ethylene Glycol

Ethylene Glycol

SCHEMBL7569310

C=C.CCOC(=O)CC(C)=O.OCCO

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.58
MGAM O43451 2/20 0.58
SI P14410 2/20 0.58
MGAM2 Q2M2H8 2/20 0.58
ALDH1A1 P00352 4/20 0.43
TRPA1 O75762 1/20 0.43
LMNA P02545 1/20 0.42
HSD17B10 Q99714 1/20 0.42
CYP4F2 P78329 1/20 0.39
CYP4A11 Q02928 1/20 0.39
CYP1A2 P05177 1/20 0.38
KDM4E B2RXH2 2/20 0.37
PKM P14618 1/20 0.37
ALOX15 P16050 2/20 0.36
SOAT1 P35610 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
TSHR P16473 1/20 0.35
MAPT P10636 1/20 0.34
CA12 O43570 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL1302700 0.96 GAA (0.64) GAAMGAMSIMGAM2ALDH1A1
Ethylene SCHEMBL28264916 0.93 GAA (0.67) GAAMGAMSIMGAM2ALDH1A1
Propanol SCHEMBL6003536 0.89 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
Formaldehyde SCHEMBL28181539 0.89 GAA (0.67) GAAMGAMSIMGAM2ALDH1A1
Alcohol SCHEMBL7251358 0.89 GAA (0.67) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL28208665 0.89 GAA (0.67) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1330478 0.89
SCHEMBL1871576 0.89 GAA (0.74) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL1332259 0.89
SCHEMBL1331762 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1229012-A1 PROCESS FOR PREPARING BETA-KETOESTER ACETAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2002-08-07 EP claimed
EP-1229012-A1 PROCESS FOR PREPARING BETA-KETOESTER ACETAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2002-08-07 EP disclosed