Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29915506 | 0.89 | MAOB (0.57) | TAAR1MAOBIDO1DAOHDAC1 | |
| SCHEMBL1011004 | 0.89 | MAOB (0.57) | TAAR1MAOBIDO1DAOHDAC1 | |
| Iodide SCHEMBL28682742 | 0.87 | MAOB (0.55) | TAAR1MAOBIDO1DAOHDAC1 | |
| Hydrochloric Acid SCHEMBL6944674 | 0.87 | MAOB (0.59) | TAAR1MAOBIDO1DAOSMN1; SMN2 | |
| SCHEMBL29423333 | 0.83 | TAAR1 (1.00) | TAAR1IDO1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL265615 | 0.83 | TAAR1 (1.00) | TAAR1IDO1SMN1; SMN2HTR2AHTR2C | |
| Bromide SCHEMBL31622102 | 0.81 | TAAR1 (0.95) | TAAR1IDO1SMN1; SMN2HTR2AHTR2C | |
| Iodide SCHEMBL28685278 | 0.81 | TAAR1 (0.95) | TAAR1IDO1SMN1; SMN2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL533785 | 0.81 | TAAR1 (0.95) | TAAR1IDO1SMN1; SMN2HTR2AHTR2C | |
| SCHEMBL2096671 | 0.78 | IDO1 (0.53) | TAAR1MAOBIDO1DAOHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144399-A3 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | Wyeth (US) | 2002-09-11 | — | — | EP | disclosed |
| EP-1144399-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000034261-A2 | HETEROCYCLIC CARBOXAMIDE-CONTAINING THIOUREA INHIBITORS OF HERPES VIRUSES CONTAINING A SUBSTITUTED PHENYLENEDIAMINE GROUP | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |