SCHEMBL1011004

SCHEMBL1011004

NCCc1ccccc1C(F)(F)F

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.57
IDO1 P14902 2/20 0.57
TAAR1 Q96RJ0 7/20 0.56
DAO P14920 1/20 0.46
HTR2A P28223 2/20 0.45
ALDH1A1 P00352 2/20 0.45
POLB P06746 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HTR2C P28335 1/20 0.44
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC8 Q9BY41 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29915506 1.00 MAOB (0.57) MAOBIDO1TAAR1DAOHTR2A
Hydrochloric Acid SCHEMBL6944674 0.98 MAOB (0.59) MAOBIDO1TAAR1DAOHTR2A
Iodide SCHEMBL28682742 0.98 MAOB (0.55) MAOBIDO1TAAR1DAOHTR2A
SCHEMBL7569592 0.89 TAAR1 (0.69) MAOBIDO1TAAR1DAOHTR2A
SCHEMBL2096671 0.88 IDO1 (0.53) MAOBIDO1TAAR1DAOALDH1A1
Acetic Acid SCHEMBL10562647 0.88 POLQ (0.50) MAOBIDO1TAAR1ALDH1A1POLB
SCHEMBL17329111 0.86 IDO1 (0.59) MAOBIDO1DAOALDH1A1POLB
Hydrochloric Acid SCHEMBL15969655 0.86 IDO1 (0.55) MAOBIDO1TAAR1DAOALDH1A1
SCHEMBL6236119 0.84 IDO1 (0.50) MAOBIDO1TAAR1DAOALDH1A1
SCHEMBL43013 0.82 IDO1 (0.61) MAOBIDO1DAOALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119410231-A Preparation method of soft and hard composite low-icing-adhesion anti-icing coating 国网山东省电力公司莱芜供电公司 2025-02-11 CN claimed
CN-115057883-B Two-dimensional perovskite white light material and preparation method and application thereof 吉林大学 2024-05-17 CN claimed
CN-112079775-B Synthesis method of 5-trifluoromethyl isoquinoline-8-formic acid 苏州康润医药有限公司 2022-11-22 CN claimed
CN-115057883-A Two-dimensional perovskite white light material and preparation method and application thereof 吉林大学 2022-09-16 CN claimed
CN-113512029-A Preparation and application of substituted pyrazole compound containing pyrimidinamine 沈阳中化农药化工研发有限公司 2021-10-19 CN claimed
CN-101410366-A Substituted bicyclic ring derivatives and uses thereof ASAHI KASEI PHARMA CORP (JP) 2009-04-15 CN claimed
EP-4725942-A1 COMPOUNDS ACTIVE ON CYCLIN D1 PATHWAY AND THEIR USE Sibylla Biotech S.p.A. (IT) 2026-04-15 EP disclosed
US-12428416-B2 ERK inhibitors and uses thereof CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2025-09-30 US disclosed
CN-119410231-B Preparation method of soft and hard composite low-icing-adhesion anti-icing coating 国网山东省电力公司莱芜供电公司 2025-08-15 CN disclosed
US-20250136545-A1 NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY GLUCOX BIOTECH AB (SE) 2025-05-01 US disclosed
CN-119410231-A Preparation method of soft and hard composite low-icing-adhesion anti-icing coating 国网山东省电力公司莱芜供电公司 2025-02-11 CN disclosed
CN-119410231-A Preparation method of soft and hard composite low-icing-adhesion anti-icing coating 国网山东省电力公司莱芜供电公司 2025-02-11 CN disclosed
EP-4499629-A1 BICYCLIC HETEROARYL-CONTAINING COMPOUNDS AS IKZF2 DEGRADERS Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2025-02-05 EP disclosed
US-5294622-A Fungicides, insecticides, miticides DOWELANCO (US) 1994-03-15 US disclosed
EP-0563132-A1 TETRAPEPTIDE DERIVATIVES AND ANALOGUES. BLACK JAMES FOUNDATION (GB) 1993-10-06 EP disclosed
WO-1992011284-A1 TETRAPEPTIDE DERIVATIVES AND ANALOGUES THE JAMES BLACK FOUNDATION LIMITED (GB) 1992-07-09 WO disclosed
US-5114939-A Amine or ether substitutes compounds of quinoline or cinnoline DOWELANCO (US) 1992-05-19 US disclosed
US-4857553-A SIDE EFFECT REDUCTION A. H. ROBINS COMPANY, INCORPORATED (US) 1989-08-15 US disclosed
EP-0326331-A2 Substituted quinolines and cinnolines DowElanco (US) 1989-08-02 EP disclosed
EP-0302757-A2 Anti-emetic serotonin depleting agents A.H. ROBINS COMPANY, INCORPORATED (US) 1989-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250136545-A1 NOVEL SULFONAMIDE DERIVATIVES HAVING SELECTIVE NOX INHIBITING ACTIVITY NOX4, NOX1, NOX5 MAOB 444/4885IDO1 2932/4885TAAR1 2787/4885
US-12428416-B2 ERK inhibitors and uses thereof MAPKAPK2, MAPK3, MAP4K2 MAOB 3835/4885IDO1 4525/4885TAAR1 4313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.