Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563806 | 0.78 | MAPK13 (0.68) | KMT2AMAPK1GAAHTTMEN1 | |
| SCHEMBL8306657 | 0.77 | KMT2A (0.58) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL7572875 | 0.74 | KMT2A (0.54) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL7039277 | 0.73 | GAA (0.61) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL5172484 | 0.72 | MAPK1 (0.60) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL5173228 | 0.72 | MAPK13 (0.61) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL7079381 | 0.72 | KMT2A (0.54) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL480106 | 0.72 | KMT2A (0.70) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL7571478 | 0.71 | MAPK14 (0.67) | KMT2AMEN1 | |
| SCHEMBL5174693 | 0.71 | KMT2A (0.56) | KMT2AMAPK1GAAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |