Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | FLT1 | P17948 | 2/20 | 0.46 |
| ▸ | FLT4 | P35916 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6985894 | 0.90 | RORC (0.52) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL7079381 | 0.82 | KMT2A (0.54) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL7039277 | 0.78 | GAA (0.61) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL5172484 | 0.77 | MAPK1 (0.60) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL5173228 | 0.77 | MAPK13 (0.61) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL7570546 | 0.77 | MAPK14 (0.72) | KMT2AMAPK1GAAHTTMAPT | |
| SCHEMBL5175977 | 0.76 | KMT2A (0.56) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL7079685 | 0.76 | CYP1A2 (0.58) | KMT2AMAPK1GAAHTTNPSR1 | |
| SCHEMBL8306939 | 0.76 | ALDH1A1 (0.55) | KMT2AHTTMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5174659 | 0.75 | MAPK1 (0.57) | KMT2AMAPK1GAAHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |