Glutarate

Glutarate

SCHEMBL7569753

CC(C)(C)COC(=O)CCCCC(=O)O.O=C(O)CCCC(=O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.52
PAM P19021 2/20 0.44
LMNA P02545 2/20 0.44
SLC22A6 Q4U2R8 2/20 0.44
NFKB1 P19838 1/20 0.42
PMP22 Q01453 1/20 0.42
AKR1B1 P15121 1/20 0.41
ALDH1A1 P00352 3/20 0.41
GPR84 Q9NQS5 6/20 0.40
PPARG P37231 6/20 0.40
PPARD Q03181 6/20 0.40
PPARA Q07869 6/20 0.40
HDAC11 Q96DB2 5/20 0.40
TLR2 O60603 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
FABP4 P15090 2/20 0.40
PTPN1 P18031 2/20 0.40
SLC22A8 Q8TCC7 1/20 0.40
MEN1 O00255 1/20 0.40
ESR1 P03372 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28682096 0.98 TSHR (0.54) TSHRPAMLMNASLC22A6NFKB1
SCHEMBL852014 0.98 TSHR (0.48) TSHRPAMLMNASLC22A6NFKB1
SCHEMBL7680019 0.96 PAM (0.48) TSHRPAMLMNASLC22A6NFKB1
SCHEMBL7047237 0.96 PAM (0.48) TSHRPAMLMNASLC22A6NFKB1
SCHEMBL27804161 0.96 PAM (0.48) TSHRPAMLMNASLC22A6NFKB1
Ethylene SCHEMBL30631590 0.94 TSHR (0.45) TSHRPAMLMNASLC22A6NFKB1
Ethylene Glycol SCHEMBL6238771 0.92 TSHR (0.44) TSHRPAMLMNASLC22A6NFKB1
Cyclohexane SCHEMBL19371333 0.92 TSHR (0.44) TSHRPAMLMNASLC22A6NFKB1
SCHEMBL18287419 0.92 TSHR (0.44) TSHRPAMLMNASLC22A6NFKB1
Hexane SCHEMBL844454 0.91 PAM (0.58) TSHRPAMSLC22A6AKR1B1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1228130-A2 IMPROVED PCT FORMULATIONS CONTAINING HALOGENATED IMIDES, SODIUM ANTIMONATE, AND REINFORCING FIBERS EASTMAN CHEMICAL COMPANY (US) 2002-08-07 EP disclosed
WO-2001025325-A2 IMPROVED PCT FORMULATIONS CONTAINING HALOGENATED IMIDES, SODIUM ANTIMONATE, AND REINFORCING FIBERS EASTMAN CHEMICAL COMPANY (US) 2001-04-12 WO disclosed
WO-2001021700-A1 PROCESS FOR IMPROVING THE MELT STABILITY OF HALOGENATED IMIDES IN PCT FORMULATIONS BY ADDITION OF SODIUM ANTIMONATE EASTMAN CHEMICAL COMPANY (US) 2001-03-29 WO disclosed