SCHEMBL7569754 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK14	Q16539	9/20	0.42

▸	MAPK13	O15264	8/20	0.42

▸	MAPK12	P53778	8/20	0.42

▸	MAPK11	Q15759	8/20	0.42

▸	MAOA	P21397	6/20	0.38

▸	MAOB	P27338	5/20	0.38

▸	CTNNB1	P35222	1/20	0.37

▸	WNT3A	P56704	1/20	0.37

▸	ULK1	O75385	1/20	0.37

▸	NOTUM	Q6P988	1/20	0.33

▸	EGFR	P00533	1/20	0.33

▸	FLT1	P17948	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7082594	0.91	MAPK14 (0.50)	MAPK14MAPK13MAPK12MAPK11MAOA
SCHEMBL7076771	0.85	MAPK14 (0.56)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL7079600	0.80	MAPK14 (0.61)	MAPK14MAPK13MAPK12MAPK11MAOA
SCHEMBL7076164	0.78	MAPK14 (0.48)	MAPK14MAPK13MAPK12MAPK11MAOA
SCHEMBL7076162	0.78	MAPK14 (0.48)	MAPK14MAPK13MAPK12MAPK11MAOA
SCHEMBL7079285	0.75	MAPK14 (0.73)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL5174459	0.72	MAPK14 (0.71)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL7082071	0.71	MAPK14 (0.54)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL7082070	0.71	MAPK14 (0.54)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL7076169	0.71	MAPK14 (0.56)	MAPK14MAPK13MAPK12MAPK11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2002083622-A2	NOVEL AMINOPHENYL KETONE DERIVATIVES	LEO PHARMA A/S (DK)	2002-10-24	—	—	WO	disclosed