Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.71 |
| ▸ | MAPK13 | O15264 | 12/20 | 0.71 |
| ▸ | MAPK12 | P53778 | 12/20 | 0.71 |
| ▸ | MAPK11 | Q15759 | 12/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.41 |
| ▸ | OXTR | P30559 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.41 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1908412 | 0.93 | MAPK14 (0.62) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL1897537 | 0.91 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL1899395 | 0.90 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11DHODH | |
| SCHEMBL1907606 | 0.90 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL1907094 | 0.90 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL1906857 | 0.89 | MAPK14 (0.64) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL7075394 | 0.87 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL1897913 | 0.87 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL1898336 | 0.87 | MAPK14 (0.56) | MAPK14MAPK13MAPK12MAPK11MAPT | |
| SCHEMBL5173177 | 0.87 | MAPK14 (0.75) | MAPK14MAPK13MAPK12MAPK11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541670-B2 | Antiinflammatory agents | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-04-01 | — | — | US | claimed |
| US-20030013770-A1 | Aminobenzophenones as inhibitors of il 1b and tnf | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-01-16 | — | — | US | claimed |
| EP-1237845-B1 | AMINOBENZOPHENONES AS INHIBITORS OF IL-1BETA AND TNF-ALPHA | LEO PHARMA AS (DK) | 2007-05-23 | — | — | EP | disclosed |
| US-6541670-B2 | Antiinflammatory agents | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-04-01 | — | — | US | disclosed |
| US-20030013770-A1 | Aminobenzophenones as inhibitors of il 1b and tnf | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013770-A1 | Aminobenzophenones as inhibitors of il 1b and tnf | IL1B, IL1A, IL6 | MAPK14 1553/4885MAPK13 2221/4885MAPK12 1892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.