Citric Acid

Citric Acid

SCHEMBL7569858

O.O=C([O-])CC(O)(CC(=O)O)C(=O)O.[K+]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACVR1ADORA1ADORA2AADORA2BADORA3ESR1ESR2FLT3GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSC1GSK3AGSK3BHRH1HRH2HTR7IDH1IDH2IMPA1IRAK1JAK1JAK2JAK3MEN1OPRM1P2RX3PDE5ASCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASIGMAR1SLC6A2SYKTACR1TOP2ATYK2

The experimentally established mechanism targets of Citric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 1/20 0.35
ALDH1A1 P00352 2/20 0.68
CA4 P22748 1/20 0.50
HMGCR P04035 1/20 0.37
CHRM1 P11229 1/20 0.37
TBXA2R P21731 1/20 0.37
ADRA1A P35348 1/20 0.37
TSHR P16473 2/20 0.37
KDM4E B2RXH2 2/20 0.37
LMNA P02545 2/20 0.37
MAPT P10636 1/20 0.37
ALOX15 P16050 1/20 0.37
SLC13A5 Q86YT5 5/20 0.36
CYP2D6 P10635 2/20 0.36
CYP2C19 P33261 1/20 0.36
HIF1A Q16665 1/20 0.36
ACLY P53396 4/20 0.35
CYP1A2 P05177 1/20 0.35
KMT2A Q03164 1/20 0.35
CPT2 P23786 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Citric Acid SCHEMBL7569447 1.00 ALDH1A1 (0.68) ALDH1A1CA4HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL7573220 1.00 ALDH1A1 (0.68) ALDH1A1CA4HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL28565770 0.98 ALDH1A1 (0.65) ALDH1A1CA4HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL21243324 0.98 ALDH1A1 (0.65) ALDH1A1CA4HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL12980693 0.98 ALDH1A1 (0.71) ALDH1A1CA4HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL29094085 0.98 ALDH1A1 (0.71) ALDH1A1CA4HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL183003 0.98 ALDH1A1 (0.71) ALDH1A1CA4HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL23320254 0.95 ALDH1A1 (0.68) ALDH1A1CA4HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL7006255 0.95 ALDH1A1 (0.68) ALDH1A1CA4HMGCRCHRM1TBXA2R
Citric Acid SCHEMBL11882611 0.95 ALDH1A1 (0.68) ALDH1A1CA4HMGCRCHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3437153-B1 ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL EOS ENERGY TECH HOLDINGS LLC (US) 2024-11-13 EP claimed
US-20180013185-A1 ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL EOS ENERGY STORAGE LLC 2018-01-11 US claimed
EP-3204977-A1 ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL Eos Energy Storage, LLC (US) 2017-08-16 EP claimed
CN-114566723-B Electrolyte for rechargeable electrochemical cells EOS能源技术控股有限责任公司 2025-03-04 CN disclosed
EP-3437153-B1 ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL EOS ENERGY TECH HOLDINGS LLC (US) 2024-11-13 EP disclosed
US-11942606-B2 Electrolyte for rechargeable electrochemical cell EOS Energy Technology Holdings, LLC (US) 2024-03-26 US disclosed
EP-4315482-A1 HALOGEN COMPLEXING AGENTS BOUND TO THE CATHODE SURFACE IN A STATIC ZINC HALIDE BATTERY EOS Energy Technology Holdings, LLC (US) 2024-02-07 EP disclosed
CN-117296189-A Halogen complexing agent combined with cathode surface in static zinc halide battery EOS能源技术控股有限责任公司 2023-12-26 CN disclosed
CN-117279631-A Composition for increasing muscle mass 国立大学法人东北大学 2023-12-22 CN disclosed
EP-3204977-B1 ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL EOS ENERGY TECH HOLDINGS LLC (US) 2023-12-20 EP disclosed
CN-115745990-A Preparation method and application of buprofezin hapten, complete antigen and antibody 中国农业科学院农业质量标准与检测技术研究所 2023-03-07 CN disclosed
WO-2017172878-A1 ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL EOS ENERGY STORAGE, LLC (US) 2017-10-05 WO disclosed
EP-3204970-A2 ELECTOLYTE COMPOSITION FOR A ZINC-HALIDE BATTERY AND BIPOLAR ELECTRODE COMPRISING A TITANIUM CARBIDE COATED CATHODE BOX Eos Energy Storage, LLC (US) 2017-08-16 EP disclosed
EP-3204968-A1 TERMINAL ASSEMBLY FOR BIPOLAR ELECTROCHEMICAL CELL OR BATTERY Eos Energy Storage, LLC (US) 2017-08-16 EP disclosed
EP-3204977-A1 ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL Eos Energy Storage, LLC (US) 2017-08-16 EP disclosed
US-20170194666-A1 ELECTROLYTE FOR RECHARGEABLE ELECTROCHEMICAL CELL CITIBANK, N.A., AS COLLATERAL AGENT 2017-07-06 US disclosed
CN-102276446-B Method for preparing potassium dihydrogen citrate (malononitrile alloy (I)) for gold plating and monohydrate thereof SANMENXIA HENGSHENG TECHNOLOGY RES DEV CO LTD 2013-04-24 CN disclosed
CN-102276446-A Method for preparing potassium dihydrogen citrate (malononitrile alloy (I)) for gold plating and monohydrate thereof SANMENXIA HENGSHENG TECHNOLOGY RES DEV CO LTD 2011-12-14 CN disclosed
US-20020045027-A1 Anti-fog resin sheet, anti-fog agent and method article DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-04-18 US disclosed
EP-1184408-A2 Anti-fog resin sheet, anti-fog agent and molded article DAINIPPON INK AND CHEMICALS, INC. (JP) 2002-03-06 EP disclosed