Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.32 |
| ▸ | MTOR | P42345 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL754378 | 0.88 | NR3C2 (0.72) | NR3C2BRD4AR | |
| SCHEMBL756352 | 0.86 | NR3C2 (0.50) | NR3C2KMT2APIK3CDGAAHPGD | |
| SCHEMBL743757 | 0.86 | NR3C2 (0.75) | NR3C2KMT2AGAAHPGDMAPK1 | |
| SCHEMBL755215 | 0.79 | NR3C2 (0.75) | NR3C2KMT2AGAAHPGDMAPK1 | |
| SCHEMBL755857 | 0.78 | NR3C2 (0.80) | NR3C2KMT2AMEN1BRD4AR | |
| SCHEMBL754783 | 0.78 | NR3C2 (0.72) | NR3C2KMT2AGAAHPGDMAPK1 | |
| SCHEMBL756244 | 0.78 | NR3C2 (0.53) | NR3C2KMT2APIK3CDGAAHPGD | |
| SCHEMBL755904 | 0.76 | NR3C2 (0.77) | NR3C2BRD4SMN1; SMN2AR | |
| SCHEMBL756493 | 0.76 | NR3C2 (0.70) | NR3C2KMT2AGAAHPGDMAPK1 | |
| SCHEMBL754306 | 0.76 | NR3C2 (0.79) | NR3C2GAAHPGDMAPK1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984345-B9 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORP (JP) | 2012-03-21 | — | — | EP | claimed |
| EP-1984345-B1 | BENZOXAZINES AND RELATED NITROGEN-CONTAINING HETEROBICYCLIC COMPOUNDS USEFUL AS MINERALOCORTICOID RECEPTOR MODULATING AGENTS | MITSUBISHI TANABE PHARMA CORP (JP) | 2011-08-31 | — | — | EP | claimed |