Methacrylic Acid

Methacrylic Acid

SCHEMBL7570281

C=C(C)C(=O)O.CC(C)(c1ccc(OCC2CO2)cc1)c1ccc(OCC2CO2)cc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.74
MEN1 O00255 4/20 0.74
KMT2A Q03164 4/20 0.74
TP53 P04637 3/20 0.74
TSHR P16473 3/20 0.74
MAPT P10636 2/20 0.74
HPGD P15428 2/20 0.74
HIF1A Q16665 2/20 0.74
CYP1A2 P05177 1/20 0.74
PPARG P37231 1/20 0.74
TDP1 Q9NUW8 1/20 0.49
PKM P14618 2/20 0.47
LMNA P02545 2/20 0.47
GAA P10253 1/20 0.47
KDM4E B2RXH2 7/20 0.43
POLB P06746 1/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
HTT P42858 1/20 0.42
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL8741404 1.00 ALDH1A1 (0.74) ALDH1A1MEN1KMT2ATP53TSHR
SCHEMBL712702 0.89 ALDH1A1 (0.68) ALDH1A1MEN1KMT2ATP53TSHR
Acrylic Acid SCHEMBL1408546 0.87 ALDH1A1 (0.74) ALDH1A1MEN1KMT2ATP53TSHR
SCHEMBL12440176 0.86 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATP53TSHR
SCHEMBL22121 0.86 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATP53TSHR
SCHEMBL13317132 0.86 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATP53TSHR
SCHEMBL17925477 0.86 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATP53TSHR
SCHEMBL31392960 0.86 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATP53TSHR
SCHEMBL12065399 0.86 ALDH1A1 (1.00) ALDH1A1MEN1KMT2ATP53TSHR
SCHEMBL7661052 0.86 ALDH1A1 (0.64) ALDH1A1MEN1KMT2ATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2821249-B1 TIRE BRIDGESTONE CORP (JP) 2017-03-29 EP disclosed
US-20150101728-A1 TIRE BRIDGESTONE CORPORATION (JP) 2015-04-16 US disclosed
EP-2821249-A1 TIRE Bridgestone Corporation (JP) 2015-01-07 EP disclosed
EP-0906351-B1 PHOTOPOLYMERIZABLE POLYESTER COMPOSITION AND PROCESS FOR THE PRODUCTION THEREOF EASTMAN CHEMICAL SWEDEN AB (SE) 2002-09-04 EP disclosed
US-6306923-B1 Ultraviolet or visible light polymerizable and/or crosslinkable maleimide-functional coating compositions SARTOMER COMPANY, INC. 2001-10-23 US disclosed
US-6127447-A RADIATION CURABLE COATING COMPOSITION INCLUDES AN EFFECTIVE AMOUNT OF CATIONIC PHOTOINITIATOR IN COMBINATION WITH A CHARGE TRANSFER COMPLEX FUSION UV SYSTEMS, INC. (US) 2000-10-03 US disclosed
US-6054502-A USEFUL AS RADIATION CURABLE COATING COMPOSITIONS; CAN BE APPLIED TO A VARIETY OF SUBSTRATES, EXAMPLES OF WHICH INCLUDE WOOD, PAPER, PARTICLEBOARD, CHIPBOARD, METALS, METALS HAVING PRIMERS THEREON, GLASS, PLASTICS, AND METALLIZED PLASTICS PPG INDUSTRIES OHIO, INC. (US) 2000-04-25 US disclosed
EP-0906351-A1 PHOTOPOLYMERIZABLE POLYESTER COMPOSITION AND PROCESS FOR THE PRODUCTION THEREOF McWhorter Technologies AB (SE) 1999-04-07 EP disclosed
WO-1997048744-A1 PHOTOPOLYMERIZABLE POLYESTER COMPOSITION AND PROCESS FOR THE PRODUCTION THEREOF MCWHORTER TECHNOLOGIES AB (SE) 1997-12-24 WO disclosed
US-5536760-A Radiation curable compositions based on unsaturated polyesters and compounds having at least two vinyl ether groups PPG INDUSTRIES, INC. (US) 1996-07-16 US disclosed
US-5391446-A A phosphazene polyene protective layer CANON KABUSHIKI KAISHA (JP) 1995-02-21 US disclosed
EP-0322808-B1 Radiation curable compositions based on unsaturated polyesters and compounds having at least two vinyl ether groups PPG INDUSTRIES INC (US) 1994-06-22 EP disclosed
EP-0464749-A1 Image holding member CANON KABUSHIKI KAISHA (JP) 1992-01-08 EP disclosed
EP-0272572-B1 METHOD FOR IMPROVING DURABILITY OF MIRRORS UTILIZING RADIATION CURABLE COATINGS PPG INDUSTRIES, INC. (US) 1991-04-17 EP disclosed
EP-0322808-A2 Radiation curable compositions based on unsaturated polyesters and compounds having at least two vinyl ether groups PPG INDUSTRIES, INC. (US) 1989-07-05 EP disclosed
US-4788108-A PHOTOPOLYMERIZATION PPG INDUSTRIES, INC. (US) 1988-11-29 US disclosed
US-4775597-A Ultraviolet light curable compositions for application to porous substrates based on unsaturated polyesters reacted with amino alcohols PPG INDUSTRIES, INC. (US) 1988-10-04 US disclosed
EP-0272572-A1 Method for improving durability of mirrors utilizing radiation curable coatings PPG INDUSTRIES, INC. (US) 1988-06-29 EP disclosed
US-4745003-A REFLECTIVE LAYER OF METAL ADHESION TO GLASS, PROTECTIVE COATINGS PPG INDUSTRIES, INC. (US) 1988-05-17 US disclosed
EP-0243501-A1 CURABLE COMPOSITION AND METHOD FOR MOLDING IT SHOWA DENKO KABUSHIKI KAISHA (JP) 1987-11-04 EP disclosed