Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7570564 | 1.00 | GHSR (0.87) | GHSRTACR1 | |
| Hydrochloric Acid SCHEMBL7566530 | 0.99 | GHSR (0.85) | GHSRTACR1 | |
| Hydrochloric Acid SCHEMBL7566534 | 0.99 | GHSR (0.85) | GHSRTACR1 | |
| Ibutamoren SCHEMBL29369919 | 0.93 | GHSR (1.00) | GHSRTACR1 | |
| Ibutamoren SCHEMBL739398 | 0.93 | GHSR (1.00) | GHSRTACR1 | |
| Ibutamoren SCHEMBL4927761 | 0.93 | GHSR (1.00) | GHSRTACR1 | |
| Ibutamoren SCHEMBL4451194 | 0.92 | GHSR (0.98) | GHSRTACR1 | |
| Ibutamoren SCHEMBL7413830 | 0.92 | GHSR (0.98) | GHSRTACR1 | |
| Ibutamoren SCHEMBL7413834 | 0.92 | GHSR (0.98) | GHSRTACR1 | |
| Ibutamoren SCHEMBL29366896 | 0.92 | GHSR (0.98) | GHSRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0615977-B1 | Spiro piperidines and homologs which promote release of growth hormone | MERCK & CO INC (US) | 2002-07-03 | — | — | EP | disclosed |
| US-5652235-A | Method of using spiro piperidines to promote the release of growth hormone | MERCK & CO., INC. (US) | 1997-07-29 | — | — | US | disclosed |
| US-5536716-A | Spiro piperidines and homologs which promote release of growth hormone | MERCK & CO., INC. (US) | 1996-07-16 | — | — | US | disclosed |
| EP-0615977-A1 | Spiro piperidines and homologs which promote release of growth hormone | MERCK & CO. INC. (US) | 1994-09-21 | — | — | EP | disclosed |