Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.43 |
| ▸ | DNM2 | P50570 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | POLR1A | O95602 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567212 | 0.86 | AOX1 (0.49) | HDAC1HDAC6AOX1HTTRAD52 | |
| SCHEMBL7567208 | 0.85 | HDAC1 (0.43) | HDAC1HDAC6AOX1KDM4EALDH1A1 | |
| SCHEMBL8415169 | 0.84 | HDAC1 (0.47) | HDAC1HDAC6AOX1DNM2PIK3CD | |
| SCHEMBL8413334 | 0.83 | RAD52 (0.54) | HDAC1HDAC6PIK3CDKDM4EALDH1A1 | |
| SCHEMBL7569545 | 0.83 | RAD52 (0.56) | HDAC1HDAC6AOX1KDM4EALDH1A1 | |
| SCHEMBL8415079 | 0.82 | RAD52 (0.50) | HDAC1HDAC6AOX1ALDH1A1KMT2A | |
| SCHEMBL7521360 | 0.82 | HDAC1 (0.52) | HDAC1HDAC6AOX1DNM2KDM4E | |
| SCHEMBL7573617 | 0.81 | HDAC1 (0.49) | HDAC1HDAC6AOX1DNM2KDM4E | |
| SCHEMBL8624357 | 0.81 | HDAC1 (0.49) | HDAC1HDAC6AOX1DNM2ADORA2A | |
| SCHEMBL7567238 | 0.80 | RAD52 (0.47) | HDAC1HDAC6AOX1PIK3CDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |