Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2961574 | 0.84 | SIGMAR1 (0.50) | SIGMAR1MC4RKMT2AMEN1TSHR | |
| SCHEMBL5190470 | 0.81 | GAA (0.47) | SIGMAR1MC4RKMT2AMEN1TSHR | |
| SCHEMBL27314788 | 0.81 | SIGMAR1 (0.53) | SIGMAR1MC4RKMT2AMEN1TSHR | |
| SCHEMBL29528022 | 0.77 | SIGMAR1 (0.53) | SIGMAR1MC4RKMT2AMEN1GAA | |
| SCHEMBL30594794 | 0.77 | SIGMAR1 (0.57) | SIGMAR1MC4RKMT2AMEN1TSHR | |
| SCHEMBL19613477 | 0.77 | OPRL1 (0.58) | SIGMAR1KMT2AMEN1TSHRGAA | |
| SCHEMBL8936204 | 0.77 | OPRL1 (0.46) | SIGMAR1MC4RKMT2AMEN1TSHR | |
| SCHEMBL951796 | 0.77 | OPRL1 (0.58) | SIGMAR1KMT2AMEN1TSHRGAA | |
| SCHEMBL11446838 | 0.76 | SIGMAR1 (0.47) | SIGMAR1KMT2AMEN1TSHRLMNA | |
| SCHEMBL27524659 | 0.76 | CYP2D6 (0.49) | SIGMAR1KMT2AMEN1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095029-B1 | PIPERAZINE DERIVATIVES INHIBITING HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | UNIV PARIS 7 DENIS DIDEROT (FR) | 2002-09-18 | — | — | EP | disclosed |