Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.70 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7571111 | 1.00 | ENPP2 (0.70) | ENPP2APEX1PPARGRAD51RAB9A | |
| SCHEMBL16272371 | 0.91 | ENPP2 (0.79) | ENPP2APEX1PPARGRAD51RAB9A | |
| SCHEMBL14358432 | 0.87 | ENPP2 (0.91) | ENPP2APEX1RAD51RAB9ANPC1 | |
| SCHEMBL9321055 | 0.87 | ENPP2 (0.91) | ENPP2APEX1RAD51RAB9ANPC1 | |
| SCHEMBL28171088 | 0.86 | ENPP2 (0.80) | ENPP2APEX1PPARGRAD51RAB9A | |
| SCHEMBL11366643 | 0.84 | HTR2A (0.47) | ENPP2MAOA | |
| SCHEMBL11366642 | 0.84 | HTR2A (0.47) | ENPP2MAOA | |
| SCHEMBL17562373 | 0.84 | ENPP2 (0.67) | ENPP2RAB9ANPC1MEN1KMT2A | |
| SCHEMBL15444364 | 0.83 | ENPP2 (0.67) | ENPP2APEX1PPARGRAD51RAB9A | |
| SCHEMBL14358454 | 0.82 | ENPP2 (0.66) | ENPP2APEX1PPARGRAD51RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002055488-A1 | ASYMMETRIC DIVINYLSTILBENE-SULPHONIC ACIDS | CIBA SPECIALTY CHEMICALS HOLDINGS INC. (CH) | 2002-07-18 | — | — | WO | disclosed |