SCHEMBL7571418

SCHEMBL7571418

C1=NCCCCCCCCC2CCCCN2CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
L3MBTL3 Q96JM7 7/20 0.37
L3MBTL1 Q9Y468 5/20 0.37
HTR6 P50406 1/20 0.37
SLC18A3 Q16572 1/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MBTD1 Q05BQ5 5/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
PHGDH O43175 1/20 0.34
MGLL Q99685 1/20 0.34
HRH3 Q9Y5N1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16164930 1.00 L3MBTL3 (0.37) L3MBTL3L3MBTL1HTR6SLC18A3MEN1
SCHEMBL20185946 1.00 L3MBTL3 (0.37) L3MBTL3L3MBTL1HTR6SLC18A3MEN1
SCHEMBL20211606 0.96 L3MBTL3 (0.37) L3MBTL3L3MBTL1HTR6SLC18A3MEN1
SCHEMBL19681394 0.96 L3MBTL3 (0.37) L3MBTL3L3MBTL1HTR6SLC18A3MEN1
SCHEMBL27220553 0.95 KDM4E (0.35) L3MBTL3L3MBTL1HTR6SLC18A3MEN1
SCHEMBL21192477 0.90 SLC18A3 (0.38) L3MBTL3L3MBTL1HTR6SLC18A3MEN1
SCHEMBL843801 0.90 L3MBTL3 (0.34) L3MBTL3L3MBTL1HTR6SLC18A3MEN1
SCHEMBL157634 0.90 KDM4E (0.34) L3MBTL3L3MBTL1HTR6SLC18A3MEN1
SCHEMBL157635 0.90 KDM4E (0.34) L3MBTL3L3MBTL1HTR6SLC18A3MEN1
SCHEMBL28479441 0.88 KDM4E (0.33) L3MBTL3L3MBTL1HTR6SLC18A3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020169264-A1 Acylation with an acryloyl group of an amino group at some point in the peptide sequence, while still attached to the solid phase support with side chain groups intact, followed by deprotecting and free radical polymerization; vaccines THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH 2002-11-14 US disclosed