Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803170 | 0.83 | MAPT (0.39) | NOS1GAACHEK1FLT3IDO1 | |
| SCHEMBL11575132 | 0.83 | NOS1 (0.52) | NOS1CHEK1FLT3PLK3MAPT | |
| SCHEMBL4951467 | 0.83 | MAPT (0.39) | NOS1GAACHEK1FLT3IDO1 | |
| SCHEMBL15717018 | 0.76 | MAPT (0.52) | GAACHEK1IDO1MAPTTDO2 | |
| SCHEMBL31190700 | 0.76 | NOS1 (0.46) | NOS1METAP2CYP1A2MKNK1 | |
| SCHEMBL23478332 | 0.76 | NOS1 (0.46) | NOS1IDO1TDO2METAP2CYP1A2 | |
| SCHEMBL17697600 | 0.76 | NOS1 (0.46) | NOS1CHEK1FLT3PLK3IDO1 | |
| SCHEMBL23518645 | 0.76 | NOS1 (0.42) | NOS1CHEK1FLT3PLK3METAP2 | |
| SCHEMBL11576660 | 0.73 | NOS1 (0.47) | NOS1CHEK1FLT3PLK3METAP2 | |
| SCHEMBL2263127 | 0.73 | BTK (0.53) | NOS1CHEK1FLT3RETLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904769-B1 | Keratin fibre dye compositions containing Indazole amine derivatives and dyeing method | OREAL (FR) | 2002-09-25 | — | — | EP | claimed |
| US-20220162381-A1 | POLYAMIDE RESIN COMPOSITION | TOYOBO CO., LTD. (JP) | 2022-05-26 | — | — | US | disclosed |
| US-20020102404-A1 | Surface-coated calcium carbonate particles, method for manufacturing same, and adhesive | SHIRAISHI KOGYO KAISHA, LTD. (JP) | 2002-08-01 | — | — | US | disclosed |
| US-6152971-A | PROCESS FOR PRODUCING THE ELECTRODE PLATE WHICH IS CAPABLE OF ECONOMICALLY FORMING AN ACTIVE MATERIAL LAYER AND A NONCOATED PORTION IN ACCORDANCE WITH A PREDETERMINED PATTERN ON A COLLECTOR SURFACE | DAI NIPPON PRINTING CO., LTD. (JP) | 2000-11-28 | — | — | US | disclosed |
| US-6027538-A | OXIDATION DYEING OF KERATINOUS FIBERS CONTAINING AT LEAST ONE COUPLER SELECTED FROM INDAZOLEAMINE DERIVATIVES AND AT LEAST ONE OXIDATION BASE; POWERFUL, NOT VERY SELECTIVE HAIR DYES WHICH ARE CAPABLE OF GENERATING INTENSE COLOR | L'OREAL S.A. (FR) | 2000-02-22 | — | — | US | disclosed |