SCHEMBL7571822

SCHEMBL7571822

N#CC=CC=CC(=O)O.[SiH3]O[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 3/20 0.33
TSHR P16473 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TP53 P04637 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11206353 0.91
SCHEMBL45721 0.91
SCHEMBL9995864 0.91
SCHEMBL30181320 0.91
SCHEMBL812499 0.89 TSHR (0.38) HCAR2TSHRMEN1KMT2ATP53
1,1-Dichloroethene SCHEMBL7776581 0.85 MEN1 (0.32) TSHRMEN1KMT2ATP53EGLN1
SCHEMBL8380503 0.84 TSHR (0.38) HCAR2TSHRMEN1KMT2ATP53
Butadiene SCHEMBL9835483 0.83 TSHR (0.33) TSHRMEN1KMT2ATP53EGLN1
Acrylic Acid Ethyl Ester SCHEMBL10811725 0.74 HCAR2 (0.49) HCAR2TSHRTP53
SCHEMBL17912275 0.73 TSHR (0.47) HCAR2TSHRMEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1240265-A2 1,1-DISUBSTITUTED ETHYLENE ADHESIVE COMPOSITIONS CONTAINING POLYDIMETHYLSILOXANE Closure Medical Corporation (US) 2002-09-18 EP disclosed
WO-2001046327-A2 1,1-DISUBSTITUTED ETHYLENE ADHESIVE COMPOSITIONS CONTAINING POLYDIMETHYLSILOXANE CLOSURE MEDICAL CORPORATION (US) 2001-06-28 WO disclosed