SCHEMBL8380503

SCHEMBL8380503

N#CC=CC(=O)O.[SiH3]O[SiH3]

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
HCAR2 Q8TDS4 4/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8799194 0.89
SCHEMBL10423 0.89
SCHEMBL996827 0.89
SCHEMBL17912275 0.89 TSHR (0.47) TSHRTP53EGLN1EGLN3HCAR2
Ammonia Solution, Strong SCHEMBL28313820 0.87
SCHEMBL11460249 0.87
Ammonia Solution, Strong SCHEMBL28308995 0.87
SCHEMBL7571822 0.84 HCAR2 (0.33) TSHRTP53EGLN1EGLN3HCAR2
Acrylic Acid SCHEMBL16468074 0.80 LMNA (0.50) TSHRTP53EGLN1EGLN3HCAR2
Phosphoric Acid SCHEMBL19260927 0.80 TSHR (0.38) TSHRTP53EGLN1EGLN3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0741127-B1 Synthesis of cyanoacrylate esters by oxidation of aromatic selenyl cyanopropionates LOCTITE CORP (US) 1999-04-07 EP disclosed
EP-0741127-A1 Synthesis of cyanoacrylate esters by oxidation of aromatic selenyl cyanopropionates LOCTITE CORPORATION (US) 1996-11-06 EP disclosed
US-5504252-A Synthesis of cyanoacrylate esters by oxidation of aromatic selenyl cyanopropionates LOCTITE CORPORATION (US) 1996-04-02 US disclosed
US-5386047-A Monomers for heat resistant, high bonding strength cyanoacrylate adhesives LOCTITE CORPORATION (US) 1995-01-31 US disclosed