Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 12/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6084569 | 0.85 | P2RX7 (1.00) | P2RX7HDAC11CNR2KMT2AMEN1 | |
| SCHEMBL21769576 | 0.80 | P2RX7 (0.63) | P2RX7HDAC11KMT2AMEN1 | |
| SCHEMBL7571956 | 0.79 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL7571999 | 0.79 | P2RX7 (0.70) | P2RX7 | |
| SCHEMBL21769577 | 0.76 | P2RX7 (0.63) | P2RX7HDAC11KMT2AMEN1 | |
| SCHEMBL5583683 | 0.75 | P2RX7 (0.59) | P2RX7HDAC11CNR2KMT2AMEN1 | |
| SCHEMBL30925378 | 0.74 | HDAC11 (1.00) | P2RX7HDAC11ALDH1A1 | |
| SCHEMBL7570486 | 0.74 | P2RX7 (0.64) | P2RX7HDAC11KMT2AMEN1ALDH1A1 | |
| SCHEMBL3454922 | 0.74 | P2RX7 (1.00) | P2RX7FAAH | |
| SCHEMBL7571057 | 0.74 | P2RX7 (1.00) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | claimed |
| EP-1036059-B1 | ADAMANTANE DERIVATIVES | ASTRAZENECA UK LTD (GB) | 2002-09-18 | — | — | EP | disclosed |