Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 4/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26145322 | 0.93 | NPC1 (0.71) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL7565407 | 0.92 | MEN1 (0.64) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2748826 | 0.87 | ALDH2 (0.67) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL31595515 | 0.85 | ALDH2 (0.76) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6142578 | 0.84 | SMN1; SMN2 (0.67) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL14107144 | 0.83 | ALDH2 (0.75) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL26145329 | 0.82 | CYP3A4 (0.62) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2750555 | 0.82 | ALDH2 (0.64) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL16458925 | 0.82 | ALDH2 (0.73) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6142590 | 0.82 | RAB9A (0.77) | ALDH2NPC1RAB9ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8178609-B2 | Isoflavones for treating mucopolysaccharidoses | INSTYTUT FARMACEUTYCZNY (PL) | 2012-05-15 | — | — | US | disclosed |
| US-20090062380-A1 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES | INSTYTUT FARMACEUTYCZNY (PL) | 2009-03-05 | — | — | US | disclosed |
| WO-2002081491-A2 | NEW GENISTEIN DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM | INSTYTUT FARMACEUTYCZNY (PL) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062380-A1 | ISOFLAVONES FOR TREATING MUCOPOLYSACCHARIDOSES | GAA, IDUA, MAN2B1 | ALDH2 3018/4885NPC1 107/4885RAB9A 3305/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.