Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SPOP | O43791 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27965816 | 1.00 | DRD2 (0.54) | DRD2PTGS2DRD3TDP1HSD17B10 | |
| SCHEMBL5718272 | 1.00 | DRD2 (0.54) | DRD2PTGS2DRD3TDP1HSD17B10 | |
| SCHEMBL29613252 | 1.00 | DRD2 (0.54) | DRD2PTGS2DRD3TDP1HSD17B10 | |
| SCHEMBL10711332 | 1.00 | DRD2 (0.54) | DRD2PTGS2DRD3TDP1HSD17B10 | |
| SCHEMBL5718275 | 1.00 | DRD2 (0.54) | DRD2PTGS2DRD3TDP1HSD17B10 | |
| SCHEMBL13608106 | 1.00 | DRD2 (0.54) | DRD2PTGS2DRD3TDP1HSD17B10 | |
| SCHEMBL3986284 | 1.00 | DRD2 (0.54) | DRD2PTGS2DRD3TDP1HSD17B10 | |
| SCHEMBL1037350 | 1.00 | DRD2 (0.54) | DRD2PTGS2DRD3TDP1HSD17B10 | |
| SCHEMBL1037351 | 1.00 | DRD2 (0.54) | DRD2PTGS2DRD3TDP1HSD17B10 | |
| SCHEMBL14195114 | 1.00 | DRD2 (0.54) | DRD2PTGS2DRD3TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528343-B1 | New process for the production of cephalosporines and novel intermediates in this process | BIOCHEMIE GMBH (AT) | 2002-09-18 | — | — | EP | claimed |
| US-5644052-A | MULTISTAGE REACTION TO PRODUCE CEPHALOSPORINS AND CHEMICAL INTERMEDIATES | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1997-07-01 | — | — | US | claimed |
| WO-1997003990-A1 | ISOMER SEPARATION | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1997-02-06 | — | — | WO | claimed |
| EP-0528343-A2 | New process for the production of cephalosporines and novel intermediates in this process | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1993-02-24 | — | — | EP | claimed |
| JP-5194533-A | — | — | None | — | — | JP | disclosed |
| WO-2015071493-A1 | CHEMOENZYMATIC SYNTHESIS OF THE CEPHALOSPORINE INTERMEDIATE 7-AMINO-3-ALKENYLCEPHEM-4-CARBOXYLIC ACID | SANDOZ AG (CH) | 2015-05-21 | — | — | WO | disclosed |
| EP-2873736-A1 | Chemoenzymatic synthesis of the cephalosporine intermediate 7-amino-3-alkenylcephem-4-carboxylic acid | Sandoz AG (CH) | 2015-05-20 | — | — | EP | disclosed |
| EP-0528343-B1 | New process for the production of cephalosporines and novel intermediates in this process | BIOCHEMIE GMBH (AT) | 2002-09-18 | — | — | EP | disclosed |
| US-6169180-B1 | NEW ECONOMICAL AND SIMPLE PROCESS, USING NEW INTERMEDIATE COMPOUND, FOR THE PRODUCTION OF 3'-SUBSTITUTED 7-AMINO-3-PROPENYL-4-CEPHEM-CARBOXYLIC ACID DERIVATIVES | BIOCHEMIE GESELLSCHAFT (AT) | 2001-01-02 | — | — | US | disclosed |
| US-6169180-B1 | NEW ECONOMICAL AND SIMPLE PROCESS, USING NEW INTERMEDIATE COMPOUND, FOR THE PRODUCTION OF 3'-SUBSTITUTED 7-AMINO-3-PROPENYL-4-CEPHEM-CARBOXYLIC ACID DERIVATIVES | BIOCHEMIE GESELLSCHAFT (AT) | 2001-01-02 | — | — | US | disclosed |
| US-5686604-A | Cephalosporines | BIOCHEMIE GESELLSCHAFT (AT) | 1997-11-11 | — | — | US | disclosed |
| US-5686604-A | Cephalosporines | BIOCHEMIE GESELLSCHAFT (AT) | 1997-11-11 | — | — | US | disclosed |
| US-5644052-A | MULTISTAGE REACTION TO PRODUCE CEPHALOSPORINS AND CHEMICAL INTERMEDIATES | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1997-07-01 | — | — | US | disclosed |
| US-5644052-A | MULTISTAGE REACTION TO PRODUCE CEPHALOSPORINS AND CHEMICAL INTERMEDIATES | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1997-07-01 | — | — | US | disclosed |
| JP-H05194533-A | NEW PRODUCTION OF CEPHALOSPORINES AND NEW INTERMEDIATE | BIOCHEM GMBH | 1993-08-03 | — | — | JP | disclosed |
| EP-0528343-A2 | New process for the production of cephalosporines and novel intermediates in this process | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1993-02-24 | — | — | EP | disclosed |
| EP-0528343-A2 | New process for the production of cephalosporines and novel intermediates in this process | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 1993-02-24 | — | — | EP | disclosed |