SCHEMBL757213

SCHEMBL757213

BrCC1=CCCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL754729 0.92
SCHEMBL11254535 0.80
SCHEMBL5320056 0.78 ALDH1A1 (0.52)
SCHEMBL16589109 0.77
SCHEMBL2513477 0.76 ALDH1A1 (0.52)
SCHEMBL9419038 0.76 ALDH1A1 (0.50)
SCHEMBL8381260 0.76 ALDH1A1 (0.52)
SCHEMBL25739975 0.75 ALDH1A1 (0.43)
SCHEMBL774686 0.74
SCHEMBL11355289 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 130 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0094102-B1 1-(1-CYCLOHEXANYL-METHYL) PYRROLIDINE DERIVATIVES, AND PROCESS FOR THEIR PREPARATION SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1985-12-27 EP claimed
EP-0094102-A2 1-(1-Cyclohexanyl-methyl) pyrrolidine derivatives, and process for their preparation SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1983-11-16 EP claimed
EP-0024960-A2 Substituted heterocyclic phenoxy amines, their preparation method and their use as local anaesthetics SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1981-03-11 EP claimed
US-20240376041-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED 2024-11-14 US disclosed
US-12129221-B2 Difluoro phenyl amide RIP1 inhibitor SIRONAX LTD (KY) 2024-10-29 US disclosed
US-12098115-B2 Methods and compositions for terpenoid synthesis UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2024-09-24 US disclosed
US-11952327-B2 Methods and compositions for terpenoid synthesis UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2024-04-09 US disclosed
US-20240025843-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2024-01-25 US disclosed
US-20240025843-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2024-01-25 US disclosed
US-20240025843-A1 METHODS AND COMPOSITIONS FOR TERPENOID SYNTHESIS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2024-01-25 US disclosed
US-20230293522-A1 HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-09-21 US disclosed
US-4594428-A Pyrrolidine compounds SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1986-06-10 US disclosed
EP-0094102-B1 1-(1-CYCLOHEXANYL-METHYL) PYRROLIDINE DERIVATIVES, AND PROCESS FOR THEIR PREPARATION SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1985-12-27 EP disclosed
US-4542134-A Derivatives of γ-butyrolactone with an anti-arrythmic activity and compositions SANOFI (FR) 1985-09-17 US disclosed
EP-0024960-B1 SUBSTITUTED HETEROCYCLIC PHENOXY AMINES, THEIR PREPARATION METHOD AND THEIR USE AS LOCAL ANAESTHETICS SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1984-12-12 EP disclosed
EP-0113600-A1 Gamma-butyrolactone derivatives with myocardium protecting and antiarrhytmic activity, process for their preparation and medicines containing them SANOFI S.A. (FR) 1984-07-18 EP disclosed
EP-0094102-A2 1-(1-Cyclohexanyl-methyl) pyrrolidine derivatives, and process for their preparation SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1983-11-16 EP disclosed
US-4379161-A Novel substituted heterocyclic phenoxyamines, the method of preparation thereof and the use thereof as local anaesthetics SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE DE FRANCE (FR) 1983-04-05 US disclosed
EP-0024960-A2 Substituted heterocyclic phenoxy amines, their preparation method and their use as local anaesthetics SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1981-03-11 EP disclosed
US-3936462-A CNS DEPRESSANT, ANALGESIC STERLING DRUG INC. (US) 1976-02-03 US disclosed