Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOX1 | Q06278 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8415114 | 0.91 | HDAC1 (0.64) | AOX1HDAC1HDAC6KLK7RAD52 | |
| SCHEMBL7568080 | 0.88 | AOX1 (0.62) | AOX1HDAC1HDAC6KLK7RAD52 | |
| SCHEMBL8415112 | 0.87 | AOX1 (0.54) | AOX1HDAC1HDAC6KLK7RAD52 | |
| SCHEMBL7570661 | 0.87 | AOX1 (0.57) | AOX1HDAC1HDAC6RAD52TMEM97 | |
| SCHEMBL8414264 | 0.85 | AOX1 (0.61) | AOX1HDAC1HDAC6RAD52KMT2A | |
| SCHEMBL8414078 | 0.84 | RAD52 (0.46) | AOX1HDAC1HDAC6RAD52KMT2A | |
| SCHEMBL7573723 | 0.84 | RAD52 (0.46) | AOX1HDAC1HDAC6RAD52KMT2A | |
| SCHEMBL7573617 | 0.84 | HDAC1 (0.49) | AOX1HDAC1HDAC6RAD52KMT2A | |
| SCHEMBL7566167 | 0.81 | AOX1 (0.55) | AOX1HDAC1HDAC6RAD52TMEM97 | |
| SCHEMBL8413595 | 0.80 | AOX1 (0.54) | AOX1HDAC1HDAC6RAD52SMARCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | claimed |