Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7568960 | 0.92 | AKR1C3 (0.58) | AKR1C3AKR1C1NPC1RAB9AFFAR4 | |
| SCHEMBL7573341 | 0.92 | AKR1C3 (0.60) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL7576366 | 0.92 | AKR1C3 (0.55) | AKR1C3AKR1C1NPC1RAB9ASLC18A3 | |
| Bicarbonate SCHEMBL7572186 | 0.87 | AKR1C3 (0.70) | AKR1C3AKR1C1NPC1RAB9ASLC18A3 | |
| SCHEMBL10895189 | 0.82 | AKR1C3 (0.61) | AKR1C3AKR1C1SLC18A3SIGMAR1GAA | |
| SCHEMBL1073107 | 0.80 | AKR1C3 (1.00) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL26144401 | 0.80 | AKR1C3 (1.00) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL17811172 | 0.80 | AKR1C3 (1.00) | AKR1C3AKR1C1NPC1RAB9ADEGS1 | |
| SCHEMBL7575974 | 0.79 | SMN1; SMN2 (0.47) | AKR1C3AKR1C1SMN1; SMN2NPSR1MAPT | |
| Bicarbonate SCHEMBL7568966 | 0.79 | AKR1C3 (0.60) | AKR1C3AKR1C1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926118-B1 | Process for the purification of bisphenols and preparation of polycarbonates therefrom | GEN ELECTRIC (US) | 2002-09-11 | — | — | EP | disclosed |
| US-6008315-A | REACTING A PHENOL AND A KETONE TO FORM BISPHENOL IN SOLUTION OR A MIXED SOLUTION OF PHENOL AND BISPHENOL, AND THE IMPROVEMENT COMPRISES FILTERING IN A NONCONTAMINATING, HEAT RESISTANT, REUSABLE CALCINED METAL FILTER | GENERAL ELECTRIC COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0926118-A1 | Process for the purification of bisphenols and preparation of polycarbonates therefrom | GENERAL ELECTRIC COMPANY (US) | 1999-06-30 | — | — | EP | disclosed |