Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572183 | 0.92 | AKR1C3 (0.67) | AKR1C3AKR1C1SMN1; SMN2NPSR1NPC1 | |
| SCHEMBL7568960 | 0.88 | AKR1C3 (0.58) | AKR1C3AKR1C1NPC1RAB9A | |
| SCHEMBL7573341 | 0.87 | AKR1C3 (0.60) | AKR1C3AKR1C1GRIN2BNPC1RAB9A | |
| Bicarbonate SCHEMBL7576375 | 0.86 | AKR1C3 (0.57) | AKR1C3AKR1C1GRIN2BSMN1; SMN2NPSR1 | |
| SCHEMBL11661537 | 0.81 | SLC18A3 (0.52) | AKR1C3AKR1C1GAAMAPTSLC18A3 | |
| SCHEMBL2766491 | 0.81 | SLC18A3 (0.52) | AKR1C3AKR1C1GAAMAPTSLC18A3 | |
| SCHEMBL26491020 | 0.79 | AKR1C3 (0.61) | AKR1C3AKR1C1GRIN2BSMN1; SMN2NPSR1 | |
| SCHEMBL7575974 | 0.78 | SMN1; SMN2 (0.47) | AKR1C3AKR1C1SMN1; SMN2NPSR1MAPT | |
| Bicarbonate SCHEMBL7572186 | 0.77 | AKR1C3 (0.70) | AKR1C3AKR1C1GRIN2BSMN1; SMN2NPC1 | |
| SCHEMBL7388336 | 0.76 | AKR1C3 (0.74) | AKR1C3AKR1C1GRIN2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0926118-B1 | Process for the purification of bisphenols and preparation of polycarbonates therefrom | GEN ELECTRIC (US) | 2002-09-11 | — | — | EP | disclosed |
| US-6008315-A | REACTING A PHENOL AND A KETONE TO FORM BISPHENOL IN SOLUTION OR A MIXED SOLUTION OF PHENOL AND BISPHENOL, AND THE IMPROVEMENT COMPRISES FILTERING IN A NONCONTAMINATING, HEAT RESISTANT, REUSABLE CALCINED METAL FILTER | GENERAL ELECTRIC COMPANY (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0926118-A1 | Process for the purification of bisphenols and preparation of polycarbonates therefrom | GENERAL ELECTRIC COMPANY (US) | 1999-06-30 | — | — | EP | disclosed |