Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.75 |
| ▸ | AR | P10275 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.66 |
| ▸ | IL1RN | P18510 | 1/20 | 0.66 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.66 |
| ▸ | KDM1A | O60341 | 1/20 | 0.63 |
| ▸ | PGR | P06401 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645822 | 0.93 | CYP19A1 (0.75) | CYP19A1ARMEN1KMT2APKM | |
| SCHEMBL16127891 | 0.86 | KMT2A (0.74) | CYP19A1MEN1KMT2APKMALDH1A1 | |
| SCHEMBL810795 | 0.84 | KMT2A (0.91) | MEN1KMT2APKMALDH1A1KEAP1 | |
| SCHEMBL7859594 | 0.84 | IDO1 (0.71) | CYP19A1ARMEN1KMT2APKM | |
| SCHEMBL11774264 | 0.84 | KMT2A (0.69) | CYP19A1ARMEN1KMT2APKM | |
| SCHEMBL96241 | 0.83 | KDM1A (0.64) | CYP19A1ARMEN1KMT2APKM | |
| SCHEMBL7572500 | 0.83 | CES1 (0.73) | CYP19A1ARALDH1A1KDM1APGR | |
| SCHEMBL6555449 | 0.83 | KDM1A (0.68) | CYP19A1ARMEN1KMT2AALDH1A1 | |
| SCHEMBL7281538 | 0.83 | KDM1A (0.68) | CYP19A1ARKDM1ACA1CA2 | |
| SCHEMBL6554559 | 0.83 | CES1 (0.73) | CYP19A1ARALDH1A1KDM1APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108822002-B | Method for synthesizing N-aryl sulfonamide under assistance of ultrasonic waves | 中南大学 | 2020-05-05 | — | — | CN | disclosed |
| CN-108822002-A | A kind of method of ultrasonic wave added synthesis N- aryl sulfonic acid amides | 中南大学 | 2018-11-16 | — | — | CN | disclosed |
| EP-1239852-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | Arrow Therapeutics Limited (GB) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001028537-A2 | BISSULFONAMIDE DERIVATIVES AS ENZYME INHIBITORS | ARROW THERAPEUTICS LIMITED (GB) | 2001-04-26 | — | — | WO | disclosed |