Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.47 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572339 | 1.00 | ALDH1A1 (0.58) | ALDH1A1NPSR1HPGDUSP2XBP1 | |
| SCHEMBL7571978 | 0.99 | ALDH1A1 (0.56) | ALDH1A1NPSR1HPGDUSP2XBP1 | |
| SCHEMBL7571980 | 0.99 | ALDH1A1 (0.56) | ALDH1A1NPSR1HPGDUSP2XBP1 | |
| SCHEMBL7572625 | 0.95 | ALDH1A1 (0.55) | ALDH1A1NPSR1HPGDUSP2XBP1 | |
| SCHEMBL7572627 | 0.95 | ALDH1A1 (0.55) | ALDH1A1NPSR1HPGDUSP2XBP1 | |
| SCHEMBL7572031 | 0.90 | MEN1 (0.51) | ALDH1A1NPSR1HPGDUSP2XBP1 | |
| SCHEMBL7572027 | 0.90 | MEN1 (0.51) | ALDH1A1NPSR1HPGDUSP2XBP1 | |
| SCHEMBL7581875 | 0.85 | ALDH1A1 (0.55) | ALDH1A1NPSR1HPGDUSP2XBP1 | |
| SCHEMBL7581881 | 0.85 | ALDH1A1 (0.55) | ALDH1A1NPSR1HPGDUSP2XBP1 | |
| SCHEMBL7579725 | 0.85 | MEN1 (0.54) | ALDH1A1NPSR1HPGDUSP2XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0810199-B1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL CO (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-5756769-A | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1998-05-26 | — | — | US | disclosed |
| EP-0810199-A1 | Method for producing propargylamine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-12-03 | — | — | EP | disclosed |