Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.58 |
| ▸ | ACE | P12821 | 13/20 | 0.58 |
| ▸ | CPA1 | P15085 | 2/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572570 | 1.00 | MME (0.58) | MMEACECPA1ACE2PTPN2 | |
| SCHEMBL8449499 | 0.93 | MME (0.49) | MMEACEPTPN1 | |
| SCHEMBL7574128 | 0.93 | MME (0.53) | MMEACECPA1ACE2 | |
| SCHEMBL7570073 | 0.93 | MME (0.53) | MMEACECPA1ACE2 | |
| SCHEMBL8017192 | 0.90 | MME (0.70) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL7566387 | 0.88 | MME (0.55) | MMEACECPA1ACE2 | |
| SCHEMBL7566393 | 0.88 | MME (0.55) | MMEACECPA1ACE2 | |
| SCHEMBL8451433 | 0.87 | MME (0.49) | MMEACECPA1ACE2 | |
| SCHEMBL7569417 | 0.87 | MME (0.56) | MMEACECPA1ACE2 | |
| SCHEMBL7569408 | 0.87 | MME (0.56) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798291-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5968980-A | ENDOPEPTIDASE 24.11 INHIBITORS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| EP-0798291-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |