Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 13/20 | 0.70 |
| ▸ | ACE | P12821 | 13/20 | 0.70 |
| ▸ | CPA1 | P15085 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8447724 | 0.94 | MME (0.69) | MMEACECPA1ACE2PPARG | |
| SCHEMBL8017254 | 0.94 | MME (0.69) | MMEACECPA1ACE2PPARG | |
| SCHEMBL9007747 | 0.94 | MME (0.61) | MMEACECPA1ACE2PPARG | |
| SCHEMBL8017292 | 0.92 | MME (0.58) | MMEACEPPARGPPARD | |
| SCHEMBL8017295 | 0.92 | MME (0.58) | MMEACEPPARGPPARD | |
| SCHEMBL8027609 | 0.92 | MME (0.66) | MMEACEPPARGPPARD | |
| SCHEMBL7572563 | 0.90 | MME (0.58) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL7572570 | 0.90 | MME (0.58) | MMEACECPA1ACE2PIN1 | |
| SCHEMBL8027099 | 0.88 | MME (0.60) | MMEACEPPARGPPARD | |
| SCHEMBL8521923 | 0.88 | MME (0.60) | MMEACEPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |