SCHEMBL757258

SCHEMBL757258

COC(=O)C1(C)CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2121481 1.00
SCHEMBL10400494 0.84 NPSR1 (0.31)
SCHEMBL20253777 0.84 NPSR1 (0.31)
SCHEMBL18028241 0.78 KDM4E (0.31)
SCHEMBL14967396 0.77 MAPK1 (0.30)
SCHEMBL19734618 0.75 ALDH1A1 (0.35)
SCHEMBL24780247 0.75 NPSR1 (0.39)
SCHEMBL2185550 0.75 NPSR1 (0.39)
SCHEMBL7929094 0.73 MEN1 (0.33)
SCHEMBL14967923 0.73 EPHX1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 CN claimed
EP-2262845-A1 MONOMERS AND POLYMERS WITH COVALENTLY-ATTACHED ACTIVE INGREDIENTS University of Southern Mississippi (US) 2010-12-22 EP claimed
US-20090208553-A1 Monomers and Polymers with Covalently - Attached Active Ingredients UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2009-08-20 US claimed
WO-2009102795-A1 MONOMERS AND POLYMERS WITH COVALENTLY-ATTACHED ACTIVE INGREDIENTS UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2009-08-20 WO claimed
US-20260146032-A1 BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS ALBIREO AB (SE) 2026-05-28 US disclosed
US-20260117026-A1 DIELECTRIC MATERIALS BASED ON HETEROAROMATIC-EXTENDED BISMALEIMIDES MERCK PATENT GMBH (DE) 2026-04-30 US disclosed
EP-4683908-A1 SUBSTITUTED OXAZOLIDINONES AND IMIDAZOLINONES AS HERBICIDES FMC Corporation (US) 2026-01-28 EP disclosed
US-12460050-B2 Nitric oxide-releasing hyperbranched compounds as antibacterial scaffolds and methods pertaining thereto THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2025-11-04 US disclosed
EP-4347575-B1 BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS ALBIREO AB (SE) 2025-07-23 EP disclosed
US-12365658-B2 Benzothia(di)azepine compounds and their use as bile acid modulators ALBIREO AB (SE) 2025-07-22 US disclosed
US-20250171459-A1 2-METHYL-4',5'-DIHYDROSPIRO[PIPERIDINE-4,7'-THIENO[2,3-C]PYRAN] DERIVATIVES AS INHIBITORS OF APOL1 AND METHODS OF USING SAME VERTEX PHARMA (US) 2025-05-29 US disclosed
CN-119708491-A Polydisulfide polymer material containing hydroxy ester group and preparation method thereof 衢州化工新材料创新研究院 2025-03-28 CN disclosed
WO-2001000608-A1 PROCESS FOR THE SYNTHESIS OF N-(4-CYANO-3-TRIFLUOROMETHYLPHENYL)-3-(4-FLUOROPHENYLSULFONYL)-2-HYDROXY-2-METHYLPROPIONAMIDE Richter Gedeon Vegyészeti Gyár Rt. (HU) 2001-01-04 WO disclosed
EP-0984959-A1 AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS MONSANTO COMPANY (US) 2000-03-15 EP disclosed
WO-1998039326-A1 AROMATIC SULFONYL ALPHA-HYDROXY HYDROXAMIC ACID COMPOUNDS MONSANTO COMPANY (US) 1998-09-11 WO disclosed
EP-0100172-B1 AMIDE DERIVATIVES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-08-12 EP disclosed
US-4636505-A ANTIANDROGENS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-01-13 US disclosed
EP-0050327-B1 PHOSPHOLIPIDS THAT CONTAIN SULPHUR, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS Roche Diagnostics GmbH (DE) 1984-06-20 EP disclosed
US-4444766-A ANTITUMOR BOEHRINGER MANNHEIM GMBH (DE) 1984-04-24 US disclosed
EP-0100172-A1 Amide derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1984-02-08 EP disclosed