Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | HTR2C | P28335 | 6/20 | 0.44 |
| ▸ | HTR2B | P41595 | 4/20 | 0.44 |
| ▸ | KMO | O15229 | 5/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | STAT6 | P42226 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6386622 | 0.89 | CHEK1 (0.44) | HTR2AHTR2CHTR2BKMORAD52 | |
| SCHEMBL6070011 | 0.85 | HTR2A (0.47) | HTR2AHTR2CHTR2BKMOHTR1A | |
| SCHEMBL20769975 | 0.83 | HTR2A (0.50) | HTR2AHTR2CHTR2BKMOHTR1A | |
| SCHEMBL7253683 | 0.83 | KMO (0.57) | HTR2AHTR2CHTR2BKMOHTR1A | |
| SCHEMBL22502397 | 0.81 | HTR2A (0.48) | HTR2AHTR2CHTR2BKMOHTR1A | |
| SCHEMBL6069750 | 0.80 | HTR2A (0.44) | HTR2AHTR2CHTR2BKMOHTR1A | |
| SCHEMBL217944 | 0.80 | HTR2A (0.45) | HTR2AHTR2CHTR2BKMORAD52 | |
| SCHEMBL31039602 | 0.80 | HTR2A (0.45) | HTR2AHTR2CHTR2BKMORAD52 | |
| SCHEMBL14320854 | 0.77 | HTR2A (0.54) | HTR2AHTR2CHTR2BKMOHTR1A | |
| SCHEMBL30833639 | 0.77 | HTR2A (0.54) | HTR2AHTR2CHTR2BKMOHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0904769-B1 | Keratin fibre dye compositions containing Indazole amine derivatives and dyeing method | OREAL (FR) | 2002-09-25 | — | — | EP | claimed |
| US-6027538-A | OXIDATION DYEING OF KERATINOUS FIBERS CONTAINING AT LEAST ONE COUPLER SELECTED FROM INDAZOLEAMINE DERIVATIVES AND AT LEAST ONE OXIDATION BASE; POWERFUL, NOT VERY SELECTIVE HAIR DYES WHICH ARE CAPABLE OF GENERATING INTENSE COLOR | L'OREAL S.A. (FR) | 2000-02-22 | — | — | US | disclosed |