SCHEMBL757295

SCHEMBL757295

CC(C)=C(OCC(C)C)O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10533329 0.82 TSHR (0.34) TSHR
SCHEMBL10533326 0.82 TSHR (0.34) TSHR
SCHEMBL10358199 0.79 TSHR (0.35) TSHR
SCHEMBL10358215 0.78 TSHR (0.34) TSHR
SCHEMBL9790193 0.77
SCHEMBL3296616 0.77 ALDH1A1 (0.38) ALDH1A1
SCHEMBL159233 0.72
SCHEMBL8961738 0.71
SCHEMBL22558136 0.71 TSHR (0.43) TSHRALDH1A1
SCHEMBL721746 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4695607-A Group transfer processes for acrylic star polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-22 US claimed
EP-1465935-B1 PIGMENT COMPOSITIONS WITH MODIFIED ATRP COPOLYMER DISPERSANTS BASF SE (DE) 2016-09-07 EP disclosed
EP-2235146-B1 BIODIESEL COLD FLOW IMPROVER BASF SE (DE) 2016-04-20 EP disclosed
US-9145354-B2 Pharmaceutical compounds ASTEX THERAPEUTICS LIMITED (GB) 2015-09-29 US disclosed
US-20150051199-A1 PHARMACEUTICAL COMPOUNDS ASTEX THERAPEUTICS LIMITED (GB) 2015-02-19 US disclosed
US-8900333-B2 Biodiesel cold flow improver BASF SE (DE) 2014-12-02 US disclosed
EP-2773615-A1 PHARMACEUTICAL COMPOUNDS Astex Therapeutics Limited (GB) 2014-09-10 EP disclosed
WO-2013064543-A1 PHARMACEUTICAL COMPOUNDS ASTEX THERAPEUTICS LIMITED (GB) 2013-05-10 WO disclosed
EP-1611197-B1 LIGHT STABILISING POLYMER DISPERSANTS IN PIGMENT DISPERSIONS BASF SE (DE) 2012-03-21 EP disclosed
US-7723425-B2 Pigment compositions with modified ATRP copolymer dispersants CIBA SPECIALTY CHEMICALS CORPORATION (US) 2010-05-25 US disclosed
EP-0248596-A2 Durable epoxy (meth) acrylic polymer with oxirane-containing terminal groups and preparation E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-09 EP disclosed
WO-1987007265-A1 ACYLATION AND SULFONATION OF SILYLKETENE ACETALS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-03 WO disclosed
EP-0243120-A2 Tough flexible polymer blends E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-10-28 EP disclosed
US-4695607-A Group transfer processes for acrylic star polymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-09-22 US disclosed
US-4659782-A NARROW POLYDISPERSITY; FLOW CONTROL AGENTS; FILMS; PLASTICS; COATINGS; AUTOMOBILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-21 US disclosed
US-4659783-A HIGH STRENGTH MOLDING MATERIALS AND COATINGS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-21 US disclosed
EP-0218436-A2 Acrylic pigment dispersant made by group transfer polymerization E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-15 EP disclosed
US-4656226-A BLOCK POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-07 US disclosed
EP-0188539-A1 ACRYLIC STAR POLYMERS. DU PONT (US) 1986-07-30 EP disclosed
WO-1986000626-A1 ACRYLIC STAR POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1986-01-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051199-A1 PHARMACEUTICAL COMPOUNDS NR1H4, HAVCR2, NR1H3 TSHR 99/4885ALDH1A1 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.