Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 14/20 | 0.61 |
| ▸ | CD38 | P28907 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27417062 | 0.88 | PARP1 (0.62) | PARP1CD38CYP3A4KCNH2KDM4E | |
| SCHEMBL5459806 | 0.85 | ALDH1A1 (0.50) | PARP1CYP3A4KDM4EALDH1A1 | |
| SCHEMBL29923361 | 0.83 | PARP1 (0.61) | PARP1CD38CYP3A4KCNH2KDM4E | |
| SCHEMBL4961753 | 0.83 | PARP1 (0.61) | PARP1CD38CYP3A4KCNH2KDM4E | |
| SCHEMBL27449613 | 0.81 | PARP1 (0.55) | PARP1CD38CYP3A4KCNH2KDM4E | |
| SCHEMBL27416308 | 0.81 | PARP1 (0.61) | PARP1CD38KDM4EALDH1A1GAA | |
| SCHEMBL7564139 | 0.80 | PARP1 (0.53) | PARP1CD38CYP3A4KCNH2ALDH1A1 | |
| SCHEMBL27539104 | 0.80 | PARP1 (0.53) | PARP1CD38KDM4EALDH1A1GAA | |
| SCHEMBL27448687 | 0.80 | PARP1 (0.53) | PARP1CD38KDM4EALDH1A1GAA | |
| SCHEMBL27419112 | 0.80 | PARP1 (0.53) | PARP1CD38CYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | claimed |
| CN-1116285-C | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2003-07-30 | — | — | CN | disclosed |
| EP-0934278-B1 | BIS(ACRIDINECARBOXAMIDE) AND BIS(PHENAZINECARBOXAMIDE) AS ANTITUMOUR AGENTS | XENOVA LTD (GB) | 2002-09-04 | — | — | EP | disclosed |
| CN-1240430-A | Bis(acridinecarboxamide) and Bis(phenazinecarboxamide) as antitumour agents | XENOVA LTD (GB) | 2000-01-05 | — | — | CN | disclosed |