Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007285 | 0.78 | HTR2A (0.41) | HTR2AMAOACYP2A6LMNAALDH1A1 | |
| SCHEMBL315078 | 0.78 | HTR2A (0.41) | HTR2ACYP2A6LMNAALDH1A1 | |
| SCHEMBL27633315 | 0.76 | HTR2A (0.40) | HTR2ACYP2A6LMNAKDM4ECYP2D6 | |
| SCHEMBL144446 | 0.75 | HTR2A (0.55) | HTR2AMAOA | |
| SCHEMBL7296999 | 0.75 | HTR2A (0.55) | HTR2AMAOA | |
| SCHEMBL15421313 | 0.75 | TAAR1 (0.45) | SLC6A2TAAR1LMNAHIF1AKDM4E | |
| SCHEMBL144445 | 0.75 | HTR2A (0.55) | HTR2AMAOA | |
| SCHEMBL19586405 | 0.75 | HTR2A (0.55) | HTR2AMAOA | |
| SCHEMBL11046694 | 0.74 | HTR2A (0.39) | HTR2ATAAR1CYP2A6LMNAALDH1A1 | |
| SCHEMBL8704500 | 0.74 | HTR2A (0.39) | HTR2ATAAR1CYP2A6LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108601832-A | The medical usage of anti-C-met antibodies-cytotoxic drug conjugate | 苏州盛迪亚生物医药有限公司 | 2018-09-28 | — | — | CN | disclosed |
| EP-0804427-B1 | LTA4 HYDROLASE INHIBITORS | SEARLE & CO (US) | 2002-09-18 | — | — | EP | disclosed |
| US-5455271-A | Using aromatic amine derivitives as mosquito insecticide | THE SCRIPPS RESEARCH INSTITUTE (US) | 1995-10-03 | — | — | US | disclosed |
| WO-1994000420-A1 | NOVEL TIGHT-BINDING INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1994-01-06 | — | — | WO | disclosed |
| US-4031087-A | INSECTICIDES | SHELL OIL COMPANY (US) | 1977-06-21 | — | — | US | disclosed |